Gene
cgasa
- ID
- ZDB-GENE-090313-23
- Name
- cyclic GMP-AMP synthase a
- Symbol
- cgasa Nomenclature History
- Previous Names
-
- cgas (1)
- mb21d1
- si:ch211-12a5.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have chromatin binding activity; cyclic-GMP-AMP synthase activity; and double-stranded DNA binding activity. Predicted to be involved in several processes, including cellular response to exogenous dsRNA; positive regulation of intracellular signal transduction; and regulation of defense response. Predicted to localize to cytosol; nucleus; and site of double-strand break. Orthologous to human CGAS (cyclic GMP-AMP synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ge et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | MAB21L/Cyclic GMP-AMP synthase-like receptor | Mab-21-like, HhH/H2TH-like domain | Mab-21-like, nucleotidyltransferase domain |
|---|---|---|---|---|
|
UniProtKB:F1QCP4
|
592 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cgas-201
(1)
|
Ensembl | 1,830 nt | ||
| mRNA |
mb21d1-202
(1)
|
Ensembl | 810 nt |
Interactions and Pathways
No data available
Plasmids
No data available