Gene
phf3
- ID
- ZDB-GENE-090313-207
- Name
- PHD finger protein 3
- Symbol
- phf3 Nomenclature History
- Previous Names
-
- si:dkey-188i13.1
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Predicted to be involved in DNA-templated transcription. Predicted to be active in nucleus. Is expressed in telencephalon. Orthologous to human PHF3 (PHD finger protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR003618 | Transcription elongation factor S-II, central domain |
| Domain | IPR012921 | Spen paralogue and orthologue SPOC, C-terminal |
| Domain | IPR019787 | Zinc finger, PHD-finger |
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Domain Details Per Protein
| Protein | Length | Spen paralogue and orthologue SPOC, C-terminal | Transcription elongation factor S-II, central domain | Transcription elongation factor S-II, central domain superfamily | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:B8A483
|
1691 | ||||||||
|
UniProtKB:A0A8M6Z9N0
|
1690 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-188I13 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_068213095 (1) | 5790 nt | ||
| Genomic | GenBank:BX005106 (1) | 216863 nt | ||
| Polypeptide | UniProtKB:B8A483 (1) | 1691 aa |
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
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