Gene
socs1b
- ID
- ZDB-GENE-090313-141
- Name
- suppressor of cytokine signaling 1b
- Symbol
- socs1b Nomenclature History
- Previous Names
-
- si:ch73-191k20.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphorylation. Predicted to localize to phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in ovarian carcinoma; prostate cancer; and urinary bladder cancer. Orthologous to human SOCS1 (suppressor of cytokine signaling 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from López-Muñoz et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lawir et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Autoinflammatory syndrome, familial, with or without immunodeficiency | 619375 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SH2 domain | SH2 domain superfamily | SOCS1, SH2 domain | SOCS box domain | SOCS box-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:E7FDH8
|
193 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
socs1b-201
(1)
|
Ensembl | 964 nt | ||
| mRNA |
socs1b-202
(1)
|
Ensembl | 632 nt |
Interactions and Pathways
No data available
Plasmids
No data available