Gene
apela
- ID
- ZDB-GENE-090313-116
- Name
- apelin receptor early endogenous ligand
- Symbol
- apela Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Enables apelin receptor binding activity and hormone activity. Involved in apelin receptor signaling pathway; gastrulation; and heart development. Acts upstream of with a positive effect on Kupffer's vesicle development. Acts upstream of or within with a positive effect on determination of heart left/right asymmetry and determination of liver left/right asymmetry. Acts upstream of or within blood vessel morphogenesis; chordate embryonic development; and gastrulation. Located in extracellular space. Is expressed in several structures, including Kupffer's vesicle; axis; heart primordium; hypoblast; and mesoderm. Orthologous to human APELA (apelin receptor early endogenous ligand).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 29 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR047853 | Apelin receptor early endogenous ligand |
Domain Details Per Protein
| Protein | Length | Apelin receptor early endogenous ligand |
|---|---|---|
|
UniProtKB:P0DMC2
|
Interactions and Pathways
No data available
Plasmids
No data available