Gene
dvl1a
- ID
- ZDB-GENE-090312-40
- Name
- dishevelled segment polarity protein 1a
- Symbol
- dvl1a Nomenclature History
- Previous Names
-
- si:dkey-223i19.4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable frizzled binding activity. Predicted to be involved in canonical Wnt signaling pathway and planar cell polarity pathway involved in neural tube closure. Predicted to act upstream of or within Wnt signaling pathway and intracellular signal transduction. Predicted to be active in cytosol. Is expressed in vertebral column. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Orthologous to human DVL1 (dishevelled segment polarity protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Costa et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant Robinow syndrome 2 | Alliance | Robinow syndrome, autosomal dominant 2 | 616331 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
Interactions and Pathways
No data available
Plasmids
No data available