Gene
rapgef3
- ID
- ZDB-GENE-090312-38
- Name
- Rap guanine nucleotide exchange factor (GEF) 3
- Symbol
- rapgef3 Nomenclature History
- Previous Names
-
- si:dkey-27m20.2
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Is expressed in neuromast. Orthologous to human RAPGEF3 (Rap guanine nucleotide exchange factor 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019804 | Ras guanine-nucleotide exchange factor, conserved site |
Domain | IPR000591 | DEP domain |
Domain | IPR000595 | Cyclic nucleotide-binding domain |
Domain | IPR000651 | Ras-like guanine nucleotide exchange factor, N-terminal |
Domain | IPR001895 | Ras guanine-nucleotide exchange factors catalytic domain |
Family | IPR008937 | Ras-like guanine nucleotide exchange factor |
Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Homologous_superfamily | IPR023578 | Ras guanine nucleotide exchange factor domain superfamily |
Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Homologous_superfamily | IPR036964 | Ras guanine-nucleotide exchange factor, catalytic domain superfamily |
Domain Details Per Protein
Protein | Length | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | DEP domain | Ras guanine-nucleotide exchange factor, catalytic domain superfamily | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ras guanine-nucleotide exchange factors catalytic domain | Ras-like guanine nucleotide exchange factor | Ras-like guanine nucleotide exchange factor, N-terminal | RmlC-like jelly roll fold | Ubiquitin-like domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:E7FDC9
|
867 | |||||||||||||
UniProtKB:A0A8M2B9K2
|
885 | |||||||||||||
UniProtKB:A0A8M3ANW0
|
856 | |||||||||||||
UniProtKB:A0A8M3B6B9
|
861 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
rapgef3-201
(1)
|
Ensembl | 3,091 nt | ||
mRNA |
rapgef3-203
(1)
|
Ensembl | 2,475 nt | ||
ncRNA |
rapgef3-002
(1)
|
Ensembl | 538 nt |
Interactions and Pathways
No data available
Plasmids
No data available