Gene
ndst3
- ID
- ZDB-GENE-090312-199
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
- Symbol
- ndst3 Nomenclature History
- Previous Names
-
- si:ch211-152j23.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have [heparan sulfate]-glucosamine N-sulfotransferase activity; deacetylase activity; and heparan sulfate N-acetylglucosaminyltransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to localize to Golgi apparatus. Is expressed in central nervous system; dermis; neural rod; olfactory placode; and pectoral fin. Orthologous to several human genes including NDST4 (N-deacetylase and N-sulfotransferase 4).
- Genome Resources
- Note
-
ndst3 is orthologous to NDST3 and NDST4. There appears to have been a tandem duplication after the divergence of ray-finned and lobe-finned fishes.
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PIR7
|
579 | ||||
|
UniProtKB:A0A8M9Q484
|
874 | ||||
|
UniProtKB:E7F825
|
874 |
Interactions and Pathways
No data available
Plasmids
No data available