Gene

kcnq5a

ID
ZDB-GENE-090312-185
Name
potassium voltage-gated channel, KQT-like subfamily, member 5a
Symbol
kcnq5a Nomenclature History
Previous Names
  • si:dkey-29l6.1
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have calmodulin binding activity and delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 46. Is expressed in central nervous system; cerebellum; optic tectum; preoptic area; and telencephalon. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnq5a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 46 Alliance Intellectual developmental disorder, autosomal dominant 46 617601
Associated With kcnq5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005821 Ion transport domain
Domain IPR013821 Potassium channel, voltage dependent, KCNQ, C-terminal
Family IPR003937 Potassium channel, voltage dependent, KCNQ
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length Ion transport domain Potassium channel, voltage dependent, KCNQ Potassium channel, voltage dependent, KCNQ, C-terminal Voltage-dependent channel domain superfamily
UniProtKB:A0A8M9QG06 938
UniProtKB:A0A8M9PYN5 1011
UniProtKB:A0A8M9QK86 1030
UniProtKB:A0A8M9QAC3 957
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kcnq5a-201 (1) Ensembl 3,353 nt
mRNA kcnq5a-202 (1) Ensembl 2,790 nt
mRNA kcnq5a-203 (1) Ensembl 518 nt
mRNA kcnq5a-204 (1) Ensembl 1,353 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations