Gene

myh7bb

ID

ZDB-GENE-090311-5

Name

myosin, heavy chain 7B, cardiac muscle, beta b

Symbol

myh7bb Nomenclature History

Previous Names

MYH14-2 (1)
si:ch211-209j10.4

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in atrium; cardiac ventricle; and heart. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human MYH7B (myosin heavy chain 7B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myh7bb Human Ortholog

No data available

Associated With myh7bb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002928	Myosin tail
Domain	IPR004009	Myosin, N-terminal, SH3-like
Homologous_superfamily	IPR008989	Myosin S1 fragment, N-terminal
Homologous_superfamily	IPR014751	DNA repair protein XRCC4-like, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	DNA repair protein XRCC4-like, C-terminal	Kinesin motor domain superfamily	Myosin, N-terminal, SH3-like	Myosin S1 fragment, N-terminal	Myosin tail	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9PFC7 InterPro	1276
UniProtKB:A0A8M9P5E5 InterPro	1712
UniProtKB:E9QF07 InterPro	1935

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	myh7bb-201 (1) Ensembl	Ensembl		5,805 nt	Select Tool ZFIN BLAST
mRNA	myh7bb-202 (1) Ensembl	Ensembl		6,253 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations