Gene

adcy6b

ID

ZDB-GENE-090127-2

Name

adenylate cyclase 6b

Symbol

adcy6b Nomenclature History

Previous Names

si:ch211-190a18.1

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have adenylate cyclase activity. Involved in myelination in peripheral nervous system. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADCY6 (adenylate cyclase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With adcy6b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Lethal congenital contracture syndrome 8	616287

Associated With adcy6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain	IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase
Domain	IPR009398	Adenylate cyclase, conserved domain
Domain	IPR032628	Adenylate cyclase, N-terminal
Family	IPR030672	Adenylate cyclase
Homologous_superfamily	IPR029787	Nucleotide cyclase

Domain Details Per Protein

Protein	Length	Adenylate cyclase	Adenylate cyclase, conserved domain	Adenylate cyclase, N-terminal	Adenylyl cyclase class-3/4/guanylyl cyclase	Adenylyl cyclase class-4/guanylyl cyclase, conserved site	Nucleotide cyclase
UniProtKB:A0A8M1RMQ6 InterPro	1174

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	adcy6b-201 (1) Ensembl	Ensembl	3,465 nt	Select Tool ZFIN BLAST
mRNA	adcy6b-203 (1) Ensembl	Ensembl	4,031 nt	Select Tool
ncRNA	adcy6b-002 (1) Ensembl	Ensembl	739 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations