Gene

dync1i2b

ID
ZDB-GENE-090121-1
Name
dynein, cytoplasmic 1, intermediate chain 2b
Symbol
dync1i2b Nomenclature History
Previous Names
  • fk28d02
  • wu:fk28d02
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to contribute to ATP-dependent microtubule motor activity, plus-end-directed. Predicted to be involved in positive regulation of ATP-dependent microtubule motor activity, plus-end-directed and transport along microtubule. Predicted to localize to cytoplasmic dynein complex. Is expressed in female organism. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dync1i2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with microcephaly and structural brain anomalies 618492
Associated With dync1i2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR025956 Cytoplasmic dynein 1 intermediate chain 1/2
Family IPR050687 Dynein Intermediate Chain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length Cytoplasmic dynein 1 intermediate chain 1/2 Dynein Intermediate Chain WD40 repeat WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A0R4IXD8 628
UniProtKB:A0A8M3B334 645
UniProtKB:A0A8M3AT17 625
UniProtKB:A0A8M3BA49 608
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations