Gene
dync1i2b
- ID
- ZDB-GENE-090121-1
- Name
- dynein, cytoplasmic 1, intermediate chain 2b
- Symbol
- dync1i2b Nomenclature History
- Previous Names
-
- fk28d02
- wu:fk28d02
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to contribute to ATP-dependent microtubule motor activity, plus-end-directed. Predicted to be involved in positive regulation of ATP-dependent microtubule motor activity, plus-end-directed and transport along microtubule. Predicted to localize to cytoplasmic dynein complex. Is expressed in female organism. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Newman et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with microcephaly and structural brain anomalies | 618492 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Family | IPR025956 | Cytoplasmic dynein 1 intermediate chain 1/2 |
Family | IPR050687 | Dynein Intermediate Chain |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
Protein | Length | Cytoplasmic dynein 1 intermediate chain 1/2 | Dynein Intermediate Chain | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:A0A0R4IXD8
|
628 | |||||
UniProtKB:A0A8M3B334
|
645 | |||||
UniProtKB:A0A8M3AT17
|
625 | |||||
UniProtKB:A0A8M3BA49
|
608 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available