Gene
igfbp2b
- ID
- ZDB-GENE-090107-3
- Name
- insulin-like growth factor binding protein 2b
- Symbol
- igfbp2b Nomenclature History
- Previous Names
-
- igfbp2a
- si:ch211-2k18.3 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits insulin-like growth factor I binding activity. Involved in negative regulation of developmental growth. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity. Is expressed in gut; kidney; liver; muscle; and ovary. Orthologous to human IGFBP2 (insulin like growth factor binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR017891 | Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site |
Domain | IPR000716 | Thyroglobulin type-1 |
Domain | IPR000867 | Insulin-like growth factor-binding protein, IGFBP |
Family | IPR012210 | Insulin-like growth factor binding protein 2 |
Family | IPR022321 | Insulin-like growth factor-binding protein family 1-6, chordata |
Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
Homologous_superfamily | IPR036857 | Thyroglobulin type-1 superfamily |
Domain Details Per Protein
Protein | Length | Growth factor receptor cysteine-rich domain superfamily | Insulin-like growth factor binding protein 2 | Insulin-like growth factor-binding protein family 1-6, chordata | Insulin-like growth factor-binding protein, IGFBP | Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site | Thyroglobulin type-1 | Thyroglobulin type-1 superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:B3F211
|
265 | |||||||
UniProtKB:M9MM96
|
265 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
igfbp2b-201
(1)
|
Havana | 1208 nt |
Interactions and Pathways
No data available
Plasmids
No data available