Gene
smg6
- ID
- ZDB-GENE-081107-52
- Name
- SMG6 nonsense mediated mRNA decay factor
- Symbol
- smg6 Nomenclature History
- Previous Names
-
- si:dkey-16f21.2
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have telomerase RNA binding activity and telomeric DNA binding activity. Involved in chordate embryonic development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to localize to cytoplasm and telomerase holoenzyme complex. Orthologous to human SMG6 (SMG6 nonsense mediated mRNA decay factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wittkopp et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002716 | PIN domain |
| Domain | IPR018834 | DNA/RNA-binding domain, Est1-type |
| Domain | IPR019458 | Telomerase activating protein Est1-like, N-terminal |
| Family | IPR045153 | Est1/Ebs1-like |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR029060 | PIN-like domain superfamily |
Domain Details Per Protein
| Protein | Length | DNA/RNA-binding domain, Est1-type | Est1/Ebs1-like | PIN domain | PIN-like domain superfamily | Telomerase activating protein Est1-like, N-terminal | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BJZ5
|
1544 |
Interactions and Pathways
No data available
Plasmids