Gene
pde4d
- ID
- ZDB-GENE-081105-16
- Name
- phosphodiesterase 4D, cAMP-specific
- Symbol
- pde4d Nomenclature History
- Previous Names
-
- si:dkey-190g11.2
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in acrodysostosis. Is expressed in brain; female organism; and head. Orthologous to human PDE4D (phosphodiesterase 4D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
acrodysostosis | Alliance | Acrodysostosis 2, with or without hormone resistance | 614613 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR023174 | 3'5'-cyclic nucleotide phosphodiesterase, conserved site |
Domain | IPR002073 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain |
Domain | IPR003607 | HD/PDEase domain |
Domain | IPR040844 | Phosphodiesterase 4 upstream conserved regions (UCR) |
Family | IPR023088 | 3'5'-cyclic nucleotide phosphodiesterase |
Homologous_superfamily | IPR036971 | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily |
Domain Details Per Protein
Protein | Length | 3'5'-cyclic nucleotide phosphodiesterase | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily | 3'5'-cyclic nucleotide phosphodiesterase, conserved site | HD/PDEase domain | Phosphodiesterase 4 upstream conserved regions (UCR) |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9Q3T2
|
703 | ||||||
UniProtKB:A0A8M3B1W5
|
769 | ||||||
UniProtKB:A0A8M3B4T1
|
726 |
Interactions and Pathways
No data available
Plasmids
No data available