Gene

ano6

ID
ZDB-GENE-081104-64
Name
anoctamin 6
Symbol
ano6 Nomenclature History
Previous Names
  • si:ch73-177h5.1
  • TMEM16F (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have protein dimerization activity. Involved in sprouting angiogenesis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wang et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Delcourt et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ano6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Scott syndrome Alliance Scott syndrome 262890
Associated With ano6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR032394 Anoctamin, dimerisation domain
Domain IPR049452 Anoctamin, transmembrane domain
Family IPR007632 Anoctamin
Domain Details Per Protein
Protein Length Anoctamin Anoctamin, dimerisation domain Anoctamin, transmembrane domain
UniProtKB:F1QNZ8 910
UniProtKB:A0A8M3AR51 810
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ano6-201 (1) Ensembl 2,733 nt
mRNA ano6-202 (1) Ensembl 4,205 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations