Gene
cux2b
- ID
- ZDB-GENE-081104-176
- Name
- cut-like homeobox 2b
- Symbol
- cux2b Nomenclature History
- Previous Names
-
- cux2
- si:ch211-218i18.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within glial cell development and retina development in camera-type eye. Predicted to be located in nucleus. Is expressed in eye; hindbrain; and telencephalon. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 67. Orthologous to human CUX2 (cut like homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Takano et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 67 | Alliance | Developmental and epileptic encephalopathy 67 | 618141 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CUT domain | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B1R7
|
1456 |
Interactions and Pathways
No data available
Plasmids
No data available