Gene

cyp3c2

ID
ZDB-GENE-081103-62
Name
cytochrome P450, family 3, subfamily c, polypeptide 2
Symbol
cyp3c2 Nomenclature History
Previous Names
  • si:dkey-21n8.3 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have steroid hydroxylase activity. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Is expressed in gill; heart; liver; nervous system; and pleuroperitoneal region. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp3c2 Human Ortholog
No data available
Associated With cyp3c2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR050705 Cytochrome P450 3A
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450 3A Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:E9QEE5 503
UniProtKB:A0A8M6Z545 268
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cyp3c3-202 (1) Ensembl 1,449 nt
mRNA cyp3c3-203 (1) Ensembl 1,580 nt
ncRNA cyp3c2-002 (1) Ensembl 533 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations