Gene
vhll
- ID
- ZDB-GENE-081022-78
- Name
- von Hippel-Lindau tumor suppressor like
- Symbol
- vhll Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to be involved in protein ubiquitination. Predicted to localize to VCB complex and nucleus. Human ortholog(s) of this gene implicated in several diseases, including pancreatic cancer (multiple); pheochromocytoma; polycythemia (multiple); renal cell carcinoma; and von Hippel-Lindau disease. Orthologous to human VHLL (VHL like) and VHL (von Hippel-Lindau tumor suppressor).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kim et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR022772 | von Hippel-Lindau disease tumour suppressor, beta/alpha domain |
Domain | IPR024048 | von Hippel-Lindau disease tumour suppressor, alpha domain |
Domain | IPR024053 | von Hippel-Lindau disease tumour suppressor, beta domain |
Homologous_superfamily | IPR036208 | VHL superfamily |
Homologous_superfamily | IPR037139 | von Hippel-Lindau disease tumour suppressor, alpha domain superfamily |
Homologous_superfamily | IPR037140 | von Hippel-Lindau disease tumour suppressor, beta domain superfamily |
Domain Details Per Protein
Protein | Length | VHL superfamily | von Hippel-Lindau disease tumour suppressor, alpha domain | von Hippel-Lindau disease tumour suppressor, alpha domain superfamily | von Hippel-Lindau disease tumour suppressor, beta/alpha domain | von Hippel-Lindau disease tumour suppressor, beta domain | von Hippel-Lindau disease tumour suppressor, beta domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:B3DHE4
|
158 |
Interactions and Pathways
No data available
Plasmids
No data available