Gene

exosc1

ID
ZDB-GENE-080926-3
Name
exosome component 1
Symbol
exosc1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in RNA processing. Predicted to localize to cytoplasm; nuclear exosome (RNase complex); and nucleolus. Orthologous to human EXOSC1 (exosome component 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Cabrera-Quio et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With exosc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pontocerebellar hypoplasia type 1F Alliance ?Pontocerebellar hypoplasia, type 1F 619304
Associated With exosc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003029 S1 domain
Domain IPR019495 Exosome complex component CSL4, C-terminal
Domain IPR025721 Exosome complex component, N-terminal domain
Family IPR039771 Exosome complex component Csl4
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Domain Details Per Protein
Protein Length Exosome complex component Csl4 Exosome complex component CSL4, C-terminal Exosome complex component, N-terminal domain Nucleic acid-binding, OB-fold S1 domain
UniProtKB:B8A4H5 194
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA exosc1-201 (1) Ensembl 612 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations