Gene

tnpo1

ID

ZDB-GENE-080819-1

Name

transportin 1

Symbol

tnpo1 Nomenclature History

Previous Names

Kapbeta2 (1)
karyopherin beta 2 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Acts upstream of or within smoothened signaling pathway and somite development. Predicted to be active in cytoplasm and nucleus. Orthologous to human TNPO1 (transportin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Han et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Han et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnpo1 Human Ortholog

No data available

Associated With tnpo1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001494	Importin-beta, N-terminal domain
Family	IPR040122	Importin beta family
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold
Repeat	IPR000357	HEAT repeat

Domain Details Per Protein

Protein	Length	Armadillo-like helical	Armadillo-type fold	HEAT repeat	Importin beta family	Importin-beta, N-terminal domain
UniProtKB:A0A8N7TD97 InterPro	891

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tnpo1-201 (1) Ensembl	Ensembl		5,804 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations