Gene
lpin1a
- ID
- ZDB-GENE-080722-2
- Name
- lipin 1a
- Symbol
- lpin1a Nomenclature History
- Previous Names
-
- lpin1
- zgc:194552
- zgc:194558
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; fatty acid catabolic process; and triglyceride biosynthetic process. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be active in mitochondrial outer membrane and nucleus. Is expressed in several structures, including head; musculature system; optic cup; paraxial mesoderm; and pectoral fin. Orthologous to human LPIN1 (lipin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Lu et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| myoglobinuria | Alliance | Myoglobinuria, acute recurrent, autosomal recessive | 268200 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | HAD-like superfamily | LIPIN family | Lipin, middle domain | Lipin/Ned1/Smp2 (LNS2) | Lipin, N-terminal | LNS2/PITP |
|---|---|---|---|---|---|---|---|
|
UniProtKB:B3DIU0
|
894 | ||||||
|
UniProtKB:X1WH54
|
920 | ||||||
|
UniProtKB:Q14EB8
|
894 |
Interactions and Pathways
No data available
Plasmids
No data available