Gene
add3b
- ID
- ZDB-GENE-080718-6
- Name
- adducin 3 (gamma) b
- Symbol
- add3b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Predicted to be involved in actin filament bundle assembly and barbed-end actin filament capping. Predicted to localize to cytoskeleton; plasma membrane raft; and postsynaptic density. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 50. Is expressed in intestine. Orthologous to human ADD3 (adducin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Tang et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spastic quadriplegic cerebral palsy 3 | Alliance | Cerebral palsy, spastic quadriplegic, 3 | 617008 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase class II Adducin subfamily | Class II aldolase/adducin N-terminal | Class II aldolase/adducin N-terminal domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M1P3L7
|
722 |
Interactions and Pathways
No data available
Plasmids
No data available