Gene

prdm13

ID

ZDB-GENE-080616-1

Name

PR domain containing 13

Symbol

prdm13 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have DNA binding activity; DNA-binding transcription factor activity; and histone methyltransferase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in nervous system. Orthologous to human PRDM13 (PR/SET domain 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Coolen et al., 2022
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prdm13 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Cerebellar dysfunction, impaired intellectual development, and hypogonadotropic hypogonadism	619761
		Pontocerebellar hypoplasia, type 17	619909

Associated With prdm13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001214	SET domain
Domain	IPR013087	Zinc finger C2H2-type
Domain	IPR044407	PRDM13, PR/SET domain
Family	IPR050717	C2H2-type Zinc-Finger Transcription Regulators
Homologous_superfamily	IPR036236	Zinc finger C2H2 superfamily
Homologous_superfamily	IPR046341	SET domain superfamily