Gene
setd1bb
- ID
- ZDB-GENE-080522-1
- Name
- SET domain containing 1B, histone lysine methyltransferase b
- Symbol
- setd1bb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and histone-lysine N-methyltransferase activity. Predicted to be involved in histone H3-K4 methylation. Predicted to localize to Set1C/COMPASS complex. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Sun et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder with seizures and language delay | 619000 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR001214 | SET domain |
| Domain | IPR003616 | Post-SET domain |
| Domain | IPR024657 | COMPASS complex Set1 subunit, N-SET domain |
| Domain | IPR037841 | Histone-lysine N-methyltransferase SETD1A/B-like, SET domain |
| Family | IPR044570 | Histone-lysine N-methyltransferase Set1-like |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
| Homologous_superfamily | IPR046341 | SET domain superfamily |
Domain Details Per Protein
| Protein | Length | COMPASS complex Set1 subunit, N-SET domain | Histone-lysine N-methyltransferase Set1-like | Histone-lysine N-methyltransferase SETD1A/B-like, SET domain | Nucleotide-binding alpha-beta plait domain superfamily | Post-SET domain | RNA-binding domain superfamily | RNA recognition motif domain | SET domain | SET domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P9Z7
|
1215 | |||||||||
|
UniProtKB:A0A8M3BBX9
|
1859 | |||||||||
|
UniProtKB:A0A8M9PZL0
|
1859 | |||||||||
|
UniProtKB:A0A8M3AVC1
|
1215 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available