Gene

nr1d4a

ID

ZDB-GENE-080403-5

Name

nuclear receptor subfamily 1, group D, member 4a

Symbol

nr1d4a Nomenclature History

Previous Names

gb:dq017622
reverbgamma-A (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and nuclear receptor transcription coactivator activity. Predicted to be involved in several processes, including hormone-mediated signaling pathway; regulation of circadian rhythm; and regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription factor complex. Is expressed in head; hindbrain; retina; retinal ganglion cell layer; and retinal inner nuclear layer.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

dq017622 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nr1d4a Human Ortholog

No data available

Associated With nr1d4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Family	IPR001728	Thyroid hormone receptor
Family	IPR050234	Nuclear hormone receptor family NR1 subfamily
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily