Gene
nfasca
- ID
- ZDB-GENE-080229-6
- Name
- neurofascin homolog (chicken) a
- Symbol
- nfasca Nomenclature History
- Previous Names
-
- sc:d0205
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; brain development; and cell-cell adhesion. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be active in axon and plasma membrane. Is expressed in nervous system; pancreatic system; and trigeminal placode. Orthologous to human NFASC (neurofascin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d205 (25 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vagionitis et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with central and peripheral motor dysfunction | 618356 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR026965 | Neurofascin, immunoglobulin-like domain |
| Domain | IPR026966 | Neurofascin/L1/NrCAM, C-terminal domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin subtype 2 | Neurofascin, immunoglobulin-like domain | Neurofascin/L1/NrCAM, C-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PUN4
|
1168 | |||||||||||
|
UniProtKB:A0A8M9QHH2
|
1379 | |||||||||||
|
UniProtKB:C0L978
|
1369 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nfasca-201
(1)
|
Ensembl | 6,288 nt | ||
| mRNA |
nfasca-202
(1)
|
Ensembl | 9,923 nt | ||
| mRNA |
nfasca-203
(1)
|
Ensembl | 4,007 nt | ||
| mRNA |
nfasca-204
(1)
|
Ensembl | 4,110 nt | ||
| mRNA |
nfasca-205
(1)
|
Ensembl | 4,066 nt |
Interactions and Pathways
No data available
Plasmids
No data available