Gene
kcnab2b
- ID
- ZDB-GENE-080219-36
- Name
- potassium voltage-gated channel subfamily A regulatory beta subunit 2b
- Symbol
- kcnab2b Nomenclature History
- Previous Names
-
- zgc:171453
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Acts upstream of or within regulation of action potential and regulation of transmission of nerve impulse. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Watanabe et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Watanabe et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023210 | NADP-dependent oxidoreductase domain |
| Family | IPR005399 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
| Family | IPR005400 | Potassium channel, voltage-dependent, beta subunit, KCNAB1 |
| Family | IPR005401 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 |
| Family | IPR005983 | Potassium channel, voltage-dependent, beta subunit, KCNAB |
| Homologous_superfamily | IPR036812 | NADP-dependent oxidoreductase domain superfamily |
Domain Details Per Protein
| Protein | Length | NADP-dependent oxidoreductase domain | NADP-dependent oxidoreductase domain superfamily | Potassium channel, voltage-dependent, beta subunit, KCNAB | Potassium channel, voltage-dependent, beta subunit, KCNAB1 | Potassium channel, voltage-dependent, beta subunit, KCNAB2 | Potassium channel, voltage-dependent, beta subunit, KCNAB-related |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PF37
|
346 | ||||||
|
UniProtKB:E9QGU5
|
412 | ||||||
|
UniProtKB:A0A8M2B927
|
454 | ||||||
|
UniProtKB:A0A8M2B9B9
|
397 | ||||||
|
UniProtKB:A0A8M9PT49
|
379 | ||||||
|
UniProtKB:A0A8M9PWJ3
|
455 | ||||||
|
UniProtKB:A0A8M2B970
|
469 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
kcnab2b-201
(1)
|
Ensembl | 1,787 nt | ||
| mRNA |
kcnab2b-202
(1)
|
Ensembl | 1,239 nt |
Interactions and Pathways
No data available
Plasmids
No data available