Gene

unc5a

ID

ZDB-GENE-080219-19

Name

unc-5 netrin receptor A

Symbol

unc5a Nomenclature History

Previous Names

zgc:175190 (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have netrin receptor activity. Predicted to be involved in anterior/posterior axon guidance. Predicted to localize to integral component of membrane. Is expressed in brain; eye; and trunk. Orthologous to human UNC5A (unc-5 netrin receptor A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from Yang et al., 2013

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With unc5a Human Ortholog

No data available

Associated With unc5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Domain	IPR033772	UPA domain
Domain	IPR042155	UNC5A, death domain
Family	IPR037936	Netrin receptor UNC5
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat

Domain Details Per Protein

Protein	Length	Death domain	Death-like domain superfamily	Immunoglobulin domain subtype	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype 2	Netrin receptor UNC5	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily	UNC5A, death domain	UPA domain	ZU5 domain
UniProtKB:A0A0R4IWL9 InterPro
UniProtKB:A0A8M9QB65 InterPro	905
UniProtKB:A9JRY6 InterPro	860
UniProtKB:A0A8M9PZC7 InterPro	916
UniProtKB:A0A8M9QGI2 InterPro	849

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	unc5a-201 (1) Ensembl	Ensembl		3,452 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations