Gene

dock5

ID

ZDB-GENE-080108-4

Name

dedicator of cytokinesis 5

Symbol

dock5 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Involved in myoblast fusion. Orthologous to human DOCK5 (dedicator of cytokinesis 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Moore et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Moore et al., 2007
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dock5 Human Ortholog

No data available

Associated With dock5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001452	SH3 domain
Domain	IPR027007	C2 DOCK-type domain
Domain	IPR027357	DOCKER domain
Domain	IPR032376	Dedicator of cytokinesis, N-terminal domain
Domain	IPR046769	DOCKER, Lobe A
Domain	IPR046770	DOCKER, Lobe B
Domain	IPR046773	DOCKER, Lobe C
Domain	IPR047025	Dedicator of cytokinesis protein 1/5, SH3 domain
Family	IPR026791	Dedicator of cytokinesis
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR042455	Dedicator of cytokinesis, N-terminal, subdomain 1
Homologous_superfamily	IPR043161	Dedicator of cytokinesis, C-terminal, lobe A
Homologous_superfamily	IPR043162	Dedicator of cytokinesis, C-terminal, lobe C