Gene
prlra
- ID
- ZDB-GENE-080103-2
- Name
- prolactin receptor a
- Symbol
- prlra Nomenclature History
- Previous Names
-
- wu:fj65c07
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have cytokine binding activity and cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Is expressed in gill; hypophysis; pancreatic bud; pronephric duct; and pronephros. Human ortholog(s) of this gene implicated in hyperprolactinemia. Orthologous to human PRLR (prolactin receptor).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Liu et al., 2006
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR003528 | Long hematopoietin receptor, single chain, conserved site |
Domain | IPR003961 | Fibronectin type III |
Domain | IPR015152 | Growth hormone/erythropoietin receptor, ligand binding |
Family | IPR050379 | Type I Cytokine Receptor |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Growth hormone/erythropoietin receptor, ligand binding | Immunoglobulin-like fold | Long hematopoietin receptor, single chain, conserved site | Type I Cytokine Receptor |
---|---|---|---|---|---|---|---|
UniProtKB:B3DI57
|
605 | ||||||
UniProtKB:A0A8M9PQC9
|
606 |
Interactions and Pathways
Plasmids
No data available