Gene
ttc12
- ID
- ZDB-GENE-071016-4
- Name
- tetratricopeptide repeat domain 12
- Symbol
- ttc12 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to be involved in axonemal dynein complex assembly and sperm axoneme assembly. Predicted to be active in centrosome and cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 45. Orthologous to human TTC12 (tetratricopeptide repeat domain 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 45 | Alliance | Ciliary dyskinesia, primary, 45 | 618801 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR043195 | Tetratricopeptide repeat protein 12 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR011990 | Tetratricopeptide-like helical domain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Repeat | IPR019734 | Tetratricopeptide repeat |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat | Tetratricopeptide repeat protein 12 |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B119
|
707 | |||||
|
UniProtKB:X1WF42
|
700 | |||||
|
UniProtKB:A0A8M3AIH8
|
443 |
Interactions and Pathways
No data available
Plasmids
No data available