Gene
ugt1a2
- ID
- ZDB-GENE-071004-5
- Name
- UDP glucuronosyltransferase 1 family, polypeptide A2
- Symbol
- ugt1a2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable glucuronosyltransferase activity. Predicted to be located in membrane. Is expressed in intestine.
- Genome Resources
-
- Alliance (1)
- Gene:100379286 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | UDP-glucuronosyl/UDP-glucosyltransferase | UDP-glycosyltransferase | UDP-glycosyltransferase family, conserved site |
|---|---|---|---|---|
|
UniProtKB:F1QM88
|
520 | |||
|
UniProtKB:A0A2R8QT48
|
||||
|
UniProtKB:D3XD47
|
295 | |||
|
UniProtKB:D3XD48
|
520 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Wang, B., Liu, L., Li, Y., Zou, J., Li, D., Zhao, D., Li, W., Sun, W. (2021) Ustilaginoidin D induces hepatotoxicity and behaviour aberrations in zebrafish larvae. Toxicology. 456:152786
- Chen, H., Chen, K., Qiu, X., Xu, H., Mao, G., Zhao, T., Feng, W., Okeke, E.S., Wu, X., Yang, L. (2020) The reproductive toxicity and potential mechanisms of combined exposure to dibutyl phthalate and diisobutyl phthalate in male zebrafish (Danio rerio). Chemosphere. 258:127238
- Christen, V., Fent, K. (2014) Tissue-, sex- and development-specific transcription profiles of eight UDP-glucuronosyltransferase genes in zebrafish (Danio rerio) and their regulation by activator of aryl hydrocarbon receptor. Aquatic toxicology (Amsterdam, Netherlands). 150:93-102
- Wang, Y., Huang, H., Wu, Q. (2014) Characterization of the Zebrafish Ugt Repertoire Reveals a New Class of Drug-metabolizing UDP Glucuronosyltransferases. Molecular pharmacology. 86(1):62-75
- Huang, H., and Wu, Q. (2010) Cloning and comparative analyses of the zebrafish ugt repertoire reveal its evolutionary diversity. PLoS One. 5(2):e9144
- Li, C., and Wu, Q. (2007) Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes. BMC Evolutionary Biology. 7(1):69
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