Gene

ppp2r3a

ID

ZDB-GENE-070912-646

Name

protein phosphatase 2, regulatory subunit B'', alpha

Symbol

ppp2r3a Nomenclature History

Previous Names

pr72 (1)
si:dkeyp-38b6.1

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable protein phosphatase regulator activity. Acts upstream of or within heart looping and sarcomere organization. Predicted to be part of protein phosphatase type 2A complex. Is expressed in brain; liver; muscle; pericardial region; and pleuroperitoneal region. Orthologous to human PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 11 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppp2r3a Human Ortholog

No data available

Associated With ppp2r3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Domain	IPR041534	PP2A regulatory subunit B'', EF-hand domain
Domain	IPR048855	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha/beta/delta, EF-hand
Homologous_superfamily	IPR011992	EF-hand domain pair

Domain Details Per Protein

Protein	Length	EF-Hand 1, calcium-binding site	EF-hand domain	EF-hand domain pair	PP2A regulatory subunit B'', EF-hand domain	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha/beta/delta, EF-hand
UniProtKB:B0S5Q0 InterPro	520
UniProtKB:E9QG28 InterPro	1192

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ppp2r3a-201 (1) Ensembl	Ensembl	4,151 nt	Select Tool ZFIN BLAST
mRNA	ppp2r3a-202 (1) Ensembl	Ensembl	3,444 nt	Select Tool ZFIN BLAST
mRNA	ppp2r3a-203 (1) Ensembl	Ensembl	5,573 nt	Select Tool ZFIN BLAST
mRNA	ppp2r3a-204 (1) Ensembl	Ensembl	4,157 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations