Gene
kcnq3
- ID
- ZDB-GENE-070912-301
- Name
- potassium voltage-gated channel, KQT-like subfamily, member 3
- Symbol
- kcnq3 Nomenclature History
- Previous Names
-
- si:ch211-66b9.3
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity and delayed rectifier potassium channel activity. Involved in chemical synaptic transmission. Predicted to localize to voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Is expressed in central nervous system; heart; and inner ear. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chege et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| benign neonatal seizures | Alliance | Seizures, benign neonatal, 2 | 121201 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ankyrin-G binding site | Ion transport domain | Potassium channel, voltage dependent, KCNQ | Potassium channel, voltage dependent, KCNQ3 | Potassium channel, voltage dependent, KCNQ, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PFX9
|
409 | |||||
|
UniProtKB:A0A8M3APZ9
|
396 | |||||
|
UniProtKB:A0A8M3AXH4
|
795 | |||||
|
UniProtKB:A0A8M9PAJ1
|
401 | |||||
|
UniProtKB:A0A8M9PQX0
|
795 |
Interactions and Pathways
No data available
Plasmids
No data available