Gene

dhx9

ID

ZDB-GENE-070912-171

Name

DEAH (Asp-Glu-Ala-His) box helicase 9

Symbol

dhx9 Nomenclature History

Previous Names

si:ch211-194i4.1
wu:fe02c10

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have 3'-5' DNA helicase activity and RNA binding activity. Involved in response to virus. Predicted to localize to nucleolus and ribonucleoprotein complex. Orthologous to human DHX9 (DExH-box helicase 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dhx9 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder, autosomal dominant 75	620988

Associated With dhx9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR002464	DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR007502	Helicase-associated domain
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR011709	DEAD-box helicase, OB fold
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR014720	Double-stranded RNA-binding domain
Domain	IPR044445	DHX9, first double-stranded RNA binding domain
Domain	IPR044446	DHX9, second double-stranded RNA binding domain
Domain	IPR044447	DHX9, DEXH-box helicase domain
Domain	IPR048333	Helicase associated domain (HA2), winged-helix domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase