Gene

map3k3

ID
ZDB-GENE-070910-1
Name
mitogen-activated protein kinase kinase kinase 3
Symbol
map3k3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Involved in anterior/posterior axis specification and heart development. Predicted to localize to cytoplasm. Orthologous to human MAP3K3 (mitogen-activated protein kinase kinase kinase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lu et al., 2018
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Hong et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With map3k3 Human Ortholog
No data available
Associated With map3k3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000270 PB1 domain
Domain IPR000719 Protein kinase domain
Domain IPR034879 Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain
Domain IPR053793 PB1-like domain
Family IPR050538 Mitogen-activated protein kinase kinase kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Mitogen-activated protein kinase kinase kinase Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain PB1 domain PB1-like domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily
UniProtKB:X1WGZ3 620
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA map3k3-201 (1) Ensembl 1,881 nt
mRNA map3k3-202 (1) Ensembl 5,003 nt
mRNA map3k3-203 (1) Ensembl 1,827 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations