Gene

dio3b

ID

ZDB-GENE-070705-53

Name

iodothyronine deiodinase 3b

Symbol

dio3b Nomenclature History

Previous Names

D3 (1)
dio3
si:ch211-156m19.1

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Exhibits thyroxine 5-deiodinase activity. Involved in several processes, including pharyngeal system development; swim bladder development; and swimming behavior. Is expressed in several structures, including brain; eye; liver; pronephros; and yolk. Orthologous to human DIO3 (iodothyronine deiodinase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

16 figures from 12 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 16 figures from 5 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dio3b Human Ortholog

No data available

Associated With dio3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008261	Iodothyronine deiodinase, active site
Family	IPR000643	Iodothyronine deiodinase
Family	IPR027252	Iodothyronine deiodinase I/III

Domain Details Per Protein

Protein	Length	Iodothyronine deiodinase	Iodothyronine deiodinase, active site	Iodothyronine deiodinase I/III
UniProtKB:A0A3G0ZGD9 InterPro	269

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
ncRNA	dio3b-001 (1) Ensembl	Ensembl		2,720 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations