Gene

epg5

ID

ZDB-GENE-070705-307

Name

ectopic P-granules autophagy protein 5 homolog (C. elegans)

Symbol

epg5 Nomenclature History

Previous Names

si:dkey-165i4.3

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to be involved in autophagy. Human ortholog(s) of this gene implicated in Vici syndrome. Orthologous to human EPG5 (ectopic P-granules autophagy protein 5 homolog).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Meneghetti et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 18 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With epg5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Vici syndrome	Alliance	Vici syndrome	242840

Associated With epg5 Via Experimental Models

Human Disease	Fish	Conditions	Citations
Vici syndrome	epg5^ia31/ia31	standard conditions	Meneghetti et al., 2019

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR051436	Autophagy-related EPG5

Domain Details Per Protein

Protein	Length	Autophagy-related EPG5
UniProtKB:A5WUT8 InterPro
UniProtKB:A0A8M3ASP3 InterPro	2546
UniProtKB:A0A8M2BCV4 InterPro	2548

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	epg5-201 (1) Ensembl	Ensembl		7,599 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations