Gene
adcy1a
- ID
- ZDB-GENE-070705-302
- Name
- adenylate cyclase 1a
- Symbol
- adcy1a Nomenclature History
- Previous Names
-
- si:dkey-162m2.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have adenylate cyclase activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and cAMP biosynthetic process. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xu et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Santos-Cortez et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 44 | Alliance | ?Deafness, autosomal recessive 44 | 610154 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adenylate cyclase | Adenylate cyclase, N-terminal | Adenylyl cyclase class-3/4/guanylyl cyclase | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Nucleotide cyclase |
|---|---|---|---|---|---|---|
|
UniProtKB:D1MIA2
|
1114 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adcy1a-201
(1)
|
Ensembl | 3,766 nt | ||
| mRNA |
adcy1a-202
(1)
|
Ensembl | 1,854 nt |
Interactions and Pathways
No data available
Plasmids
No data available