Gene

flrt2

ID

ZDB-GENE-070705-267

Name

fibronectin leucine rich transmembrane protein 2

Symbol

flrt2 Nomenclature History

Previous Names

sc:d0374
si:ch73-312h4.1 (1)
si:ct990627.1

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have fibroblast growth factor receptor binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway and positive regulation of synapse assembly. Predicted to localize to extracellular space. Is expressed in brain; neurons; pronephros; and solid lens vesicle. Orthologous to human FLRT2 (fibronectin leucine rich transmembrane protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d0374 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With flrt2 Human Ortholog

No data available

Associated With flrt2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000372	Leucine-rich repeat N-terminal domain
Domain	IPR000483	Cysteine-rich flanking region, C-terminal
Domain	IPR003961	Fibronectin type III
Family	IPR050333	Small Leucine-Rich Proteoglycans
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	Cysteine-rich flanking region, C-terminal	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat N-terminal domain	Leucine-rich repeat, typical subtype	Small Leucine-Rich Proteoglycans
UniProtKB:A0A8M1NFA3 InterPro	662
UniProtKB:X1WEV4 InterPro	662

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	flrt2-201 (1) Ensembl	Ensembl		7,961 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations