Gene
xpo1b
- ID
- ZDB-GENE-070530-6
- Name
- exportin 1 (CRM1 homolog, yeast) b
- Symbol
- xpo1b Nomenclature History
- Previous Names
-
- xpo1
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable nuclear export signal receptor activity. Acts upstream of or within response to yeast. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in colorectal cancer; gastric adenocarcinoma; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human XPO1 (exportin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001494 | Importin-beta, N-terminal domain |
| Domain | IPR013598 | Exportin-1/Importin-beta-like |
| Domain | IPR014877 | Exportin-1, C-terminal |
| Family | IPR045065 | Exportin-1/5 |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Repeat | IPR040485 | Exportin-1, repeat 3 |
| Repeat | IPR041123 | Chromosome region maintenance repeat |
| Repeat | IPR041235 | Exportin-1, repeat 2 |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Chromosome region maintenance repeat | Exportin-1/5 | Exportin-1, C-terminal | Exportin-1/Importin-beta-like | Exportin-1, repeat 2 | Exportin-1, repeat 3 | Importin-beta, N-terminal domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PPG9
|
1071 |
Interactions and Pathways
No data available
Plasmids
No data available