Gene
atp5if1a
- ID
- ZDB-GENE-070410-36
- Name
- ATP synthase inhibitory factor subunit 1a
- Symbol
- atp5if1a Nomenclature History
- Previous Names
-
- atpif1
- atpif1a
- pnt
- zgc:162207
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable ATPase binding activity; ATPase inhibitor activity; and protein homodimerization activity. Involved in erythrocyte differentiation and heme biosynthetic process. Acts upstream of or within optokinetic behavior; regulation of neuroinflammatory response; and visual perception. Predicted to be active in mitochondrion. Is expressed in blood and common myeloid progenitor. Used to study blindness. Orthologous to human ATP5IF1 (ATP synthase inhibitory factor subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Shah et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| blindness | atp5if1atq209/tq209 | standard conditions | Martín-Jiménez et al., 2018 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR007648 | Mitochondrial ATPase inhibitor |
Domain Details Per Protein
| Protein | Length | Mitochondrial ATPase inhibitor |
|---|---|---|
|
UniProtKB:A3KNL5
|
105 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
atp5if1a-202
(1)
|
Ensembl | 515 nt | ||
| mRNA |
atp5if1a-201
(1)
|
Ensembl | 530 nt |
Interactions and Pathways
No data available
Plasmids
No data available