Gene
adrb2b
- ID
- ZDB-GENE-070410-32
- Name
- adrenoceptor beta 2, surface b
- Symbol
- adrb2b Nomenclature History
- Previous Names
-
- zgc:162188
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have adrenergic receptor activity. Involved in regulation of heart rate. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); kidney failure (multiple); lung disease (multiple); and open-angle glaucoma (multiple). Is expressed in several structures, including digestive system; eye; heart; kidney; and musculature system. Orthologous to human ADRB2 (adrenoceptor beta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Beta-2-adrenoreceptor agonist, reduced response to |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adrenoceptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|
|
UniProtKB:A4QNV7
|
409 | |||
|
UniProtKB:A0A8M9PI29
|
409 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb2b-201
(1)
|
Ensembl | 3,764 nt |
Interactions and Pathways
No data available
Plasmids
No data available