Gene

faslg

ID
ZDB-GENE-070410-16
Name
Fas ligand (TNF superfamily, member 6)
Symbol
faslg Nomenclature History
Previous Names
  • FasL (1)
  • zgc:162027
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have tumor necrosis factor receptor binding activity. Involved in notochord development. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including cholangiocarcinoma; chronic myeloid leukemia; diabetes mellitus (multiple); pancreatic cancer (multiple); and pre-eclampsia (multiple). Is expressed in brain; eye; gut; notochord; and ovary. Orthologous to human FASLG (Fas ligand).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ferrari et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With faslg Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autoimmune lymphoproliferative syndrome Alliance Autoimmune lymphoproliferative syndrome, type IB 601859
lung cancer Alliance {Lung cancer, susceptibility to} 211980
Associated With faslg Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006052 Tumour necrosis factor domain
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Domain Details Per Protein
Protein Length Tumour necrosis factor domain Tumour necrosis factor-like domain superfamily
UniProtKB:Q0PKX7 268
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations