Gene

camk2g2

ID

ZDB-GENE-070323-2

Name

calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2

Symbol

camk2g2 Nomenclature History

Previous Names

CAMK2Ga (1)
camk2gb
zmp:0000000658 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have calmodulin binding activity and calmodulin-dependent protein kinase activity. Involved in response to hypoxia. Predicted to localize to cytoplasm and neuron projection. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Is expressed in brain; liver; retina; and trunk. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Francescatto et al., 2010
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With camk2g2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Intellectual developmental disorder, autosomal dominant 59	618522

Associated With camk2g2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR013543	Calcium/calmodulin-dependent protein kinase II, association-domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR032710	NTF2-like domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/calmodulin-dependent protein kinase II, association-domain	NTF2-like domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:A0A8M9QAA5 InterPro	513
UniProtKB:A0A8M9QFX6 InterPro	554
UniProtKB:A0A8M9QAB1 InterPro	347
UniProtKB:A0A8M2B390 InterPro	596
UniProtKB:A0A8M2B3U7 InterPro	585
UniProtKB:A0A8M2B3P7 InterPro	626
UniProtKB:A0A8M9QK67 InterPro	525
UniProtKB:A0A8M9QFW7 InterPro	584
UniProtKB:A0A8M9PU56 InterPro	590
UniProtKB:A0A8M9QNR7 InterPro	543
UniProtKB:A0A8M2B2Z3 InterPro	504
UniProtKB:A0A8M9Q194 InterPro	611
UniProtKB:A0A8M9Q1A2 InterPro	504
UniProtKB:A0A8M9PU60 InterPro	525
UniProtKB:A0A8M9QFW0 InterPro	611
UniProtKB:A0A8M9QK60 InterPro	569
UniProtKB:A0A8M9QNS6 InterPro	481
UniProtKB:A0A8M2B3Q3 InterPro	540
UniProtKB:A0A8M9QFY6 InterPro	489
UniProtKB:A0A8M3B830 InterPro	623
UniProtKB:A0A8M9QNR4 InterPro	572
UniProtKB:A0A8M9QFY3 InterPro	510
UniProtKB:A0A8M9QNR1 InterPro	582
UniProtKB:A0A8M2B3U9 InterPro	362
UniProtKB:A0A8M9PYL0 InterPro	502
UniProtKB:A0A8M9QK76 InterPro	637
UniProtKB:A0A8M9PYK5 InterPro	519
UniProtKB:A0A8M9QA96 InterPro	557
UniProtKB:A0A8M2B329 InterPro	605
UniProtKB:A0A8M9QK73 InterPro	478
UniProtKB:A0A8M3AZ91 InterPro	499
UniProtKB:A0A8M9QK51 InterPro	608
UniProtKB:A0A8M3BEQ5 InterPro	525
UniProtKB:A0A8M9QFZ0 InterPro	347
UniProtKB:A0A8M9QAA1 InterPro	528
UniProtKB:F1QW17 InterPro	587
UniProtKB:A0A8M3AZ56 InterPro	564
UniProtKB:A0A8M9QFW3 InterPro	593
UniProtKB:A0A8M9PYJ1 InterPro	579
UniProtKB:A0A8M9QK64 InterPro	543
UniProtKB:A0A8M9QK53 InterPro	590
UniProtKB:A0A8M3BEQ1 InterPro	575
UniProtKB:A0A8M9QNS9 InterPro	321
UniProtKB:A0A8M9Q199 InterPro	582

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	camk2g2-201 (1) Ensembl	Ensembl	1,764 nt	Select Tool ZFIN BLAST
mRNA	camk2g2-202 (1) Ensembl	Ensembl	1,914 nt	Select Tool ZFIN BLAST
mRNA	camk2g2-203 (1) Ensembl	Ensembl	4,506 nt	Select Tool ZFIN BLAST
ncRNA	camk2g2-003 (1) Ensembl	Ensembl	795 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations