Gene
dgkb
- ID
- ZDB-GENE-070126-1
- Name
- diacylglycerol kinase, beta
- Symbol
- dgkb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable diacylglycerol kinase activity. Predicted to be involved in diacylglycerol metabolic process; intracellular signal transduction; and lipid phosphorylation. Predicted to act upstream of or within phosphorylation and protein kinase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human DGKB (diacylglycerol kinase beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from O'Hare et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018247 | EF-Hand 1, calcium-binding site |
| Domain | IPR000756 | Diacylglycerol kinase, accessory domain |
| Domain | IPR001206 | Diacylglycerol kinase, catalytic domain |
| Domain | IPR002048 | EF-hand domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR029477 | Diacylglycerol kinase type I, N-terminal |
| Domain | IPR047470 | Diacylglycerol kinase beta, second protein kinase C conserved region 1 |
| Domain | IPR047471 | Diacylglycerol kinase beta-like, first protein kinase C conserved region 1 |
| Family | IPR037607 | Diacylglycerol kinase |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR016064 | NAD kinase/diacylglycerol kinase-like domain superfamily |
| Homologous_superfamily | IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal |
| Homologous_superfamily | IPR038199 | DGK type I, N-terminal domain superfamily |
| Homologous_superfamily | IPR046349 | C1-like domain superfamily |
Domain Details Per Protein
| Protein | Length | C1-like domain superfamily | DGK type I, N-terminal domain superfamily | Diacylglycerol kinase | Diacylglycerol kinase, accessory domain | Diacylglycerol kinase beta-like, first protein kinase C conserved region 1 | Diacylglycerol kinase beta, second protein kinase C conserved region 1 | Diacylglycerol kinase, catalytic domain | Diacylglycerol kinase type I, N-terminal | EF-Hand 1, calcium-binding site | EF-hand domain | EF-hand domain pair | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | NAD kinase/diacylglycerol kinase-like domain superfamily | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P7J8
|
786 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance