Gene

sesn2

ID
ZDB-GENE-070108-1
Name
sestrin 2
Symbol
sesn2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and negative regulation of TORC1 signaling. Predicted to colocalize with GATOR2 complex; TORC2 complex; and cytoplasm. Orthologous to human SESN2 (sestrin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Scheldeman et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sesn2 Human Ortholog
No data available
Associated With sesn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR006730 Sestrin
Homologous_superfamily IPR029032 AhpD-like
Domain Details Per Protein
Protein Length AhpD-like Sestrin
UniProtKB:A0F081 444
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sesn2-201 (1) Ensembl 1,931 nt
mRNA sesn2-202 (1) Ensembl 836 nt
mRNA sesn2-203 (1) Ensembl 877 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations