Gene
tnxba
- ID
- ZDB-GENE-070103-5
- Name
- tenascin XBa
- Symbol
- tnxba Nomenclature History
- Previous Names
-
- tnxb
- si:dkey-8k3.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and vesicoureteral reflux. Orthologous to human TNXB (tenascin XB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ehlers-Danlos syndrome classic-like 1 | Alliance | Ehlers-Danlos syndrome, classic-like, 1 | 606408 |
| vesicoureteral reflux | Alliance | Vesicoureteral reflux 8 | 615963 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020837 | Fibrinogen, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR013111 | EGF-like domain, extracellular |
| Domain | IPR041161 | Tenascin, EGF-like domain |
| Family | IPR050991 | Extracellular Matrix Regulatory Proteins |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Length | EGF-like domain | EGF-like domain, extracellular | Extracellular Matrix Regulatory Proteins | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen, conserved site | Fibrinogen-like, C-terminal | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold | Tenascin, EGF-like domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P891
|
2285 | |||||||||||
|
UniProtKB:A0A8M9PMY3
|
851 | |||||||||||
|
UniProtKB:A0A8M9PDJ3
|
2116 |
Interactions and Pathways
No data available
Plasmids
No data available