Gene
tmie
- ID
- ZDB-GENE-061207-9
- Name
- transmembrane inner ear
- Symbol
- tmie Nomenclature History
- Previous Names
-
- si:ch211-163f10.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Involved in posterior lateral line neuromast primordium migration; sensory organ development; and sensory perception of sound. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 6 and sensorineural hearing loss. Is expressed in brain and otic vesicle. Orthologous to human TMIE (transmembrane inner ear).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 6 | Alliance | Deafness, autosomal recessive 6 | 600971 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR032006 | Transmembrane inner ear expressed protein |
Domain Details Per Protein
| Protein | Length | Transmembrane inner ear expressed protein |
|---|---|---|
|
UniProtKB:D2ITC5
|
231 | |
|
UniProtKB:A2AVI6
|
175 | |
|
UniProtKB:A0A8M9Q9E3
|
125 |
Interactions and Pathways
No data available
Plasmids
No data available