Gene
evi5l
- ID
- ZDB-GENE-061207-24
- Name
- ecotropic viral integration site 5 like
- Symbol
- evi5l Nomenclature History
- Previous Names
-
- si:ch211-239f4.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within regulation of GTPase activity. Is expressed in telencephalon. Orthologous to human EVI5L (ecotropic viral integration site 5 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
la028159Tg | Transgenic insertion | Unknown | Unknown | DNA | |
la028160Tg | Transgenic insertion | Unknown | Unknown | DNA | |
sa12742 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa15533 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa17572 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa17798 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa19554 | Allele with one point mutation | Unknown | Splice Site | ENU | |
sa32739 | Allele with one point mutation | Unknown | Splice Site | ENU | |
zko876a | Allele with one delins | Unknown | Unknown | CRISPR | |
zko876b | Allele with one delins | Unknown | Unknown | CRISPR |
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Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000195 | Rab-GAP-TBC domain |
Domain | IPR013087 | Zinc finger C2H2-type |
Family | IPR050302 | Rab GTPase-activating TBC domain-containing protein |
Homologous_superfamily | IPR035969 | Rab-GAP-TBC domain superfamily |
Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
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Domain Details Per Protein
Protein | Length | Rab-GAP-TBC domain | Rab-GAP-TBC domain superfamily | Rab GTPase-activating TBC domain-containing protein | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
---|---|---|---|---|---|---|
UniProtKB:A0A8M3ARW8
|
985 | |||||
UniProtKB:A0A8M3AUU5
|
996 | |||||
UniProtKB:A0A8M9Q053
|
964 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-239F4 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_009293538 (1) | |||
Genomic | GenBank:AL953855 (1) | 146080 nt | ||
Polypeptide | UniProtKB:A0A8M3AUU5 (1) | 996 aa |
- Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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